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Cilique ®

Cilique is a combined hormonal contraceptive pill, used to prevent unexpected pregnancy.

Getting your pill shouldn’t be difficult. Subscribe to EveAdam and buy Cilique online. You’ll get a regular supply delivered to your door from a UK pharmacy.

Treatments from only £6.00 per month

Buy Cilique online on subscription and never run out again.

Cilique is a combined birth control pill, which means it contains two hormones, an oestrogen and a progestogen. These hormones help protect you against unexpected pregnancy. They’re also great for regulating periods and improving skin concerns like acne.

EveAdam offers Cilique and other prescriptions by subscription, ordered online and delivered right to your door. Why? Because getting a package in the mail is a nice surprise. Real talk, though? Because we believe you shouldn’t have to worry about running out of birth control.

Signing up with us is simple. After a quick consultation with a licensed doctor, you’ll receive a prescription for Cilique and choose a shipment plan where you let us know how often you’d like your pills sent to you. We pass that info on to our preferred pharmacy, and your prescription is in the mail. That’s it.

Are Cilique and Cilest the same pill?

Pretty much, yes. Cilest was discontinued by Janssen, but Cilique is made by the same people, and has the exact same hormones in it and the same amounts. So there shouldn’t be any difference between the two (fun fact: the pills are even the same colour).

If you used to take Cilest and found it helpful, but haven’t been able to find a replacement pill, Cilique might be a good option for you.

Is Cilique generic?

Yes. Cilique is the generic for the Cilest pill and another pill called Lizinna. They’re all MHRA-approved combined birth control pills. Generic versions of pills (like contraceptive pills) are tested in the same ways and are safe to use. If you have any questions about Cilique and generic versions of medication, you can talk to the clinician about this.

Can Cilique help with acne?

Many women have found that Cilique has been able to help with severe acne. Generally, birth control pills can help with acne problems.[1]

But it isn’t a given that Cilique will help with your acne.

If the problem hasn’t improved after a few months of using Cilique, it might not be the right option for you when it comes to acne relief.

It’s also worth noting that acne can be a side effect of Cilique. Keep an eye on your skin when you take the pills and if things are changing (and not in the direction you’d like!) talk to an EveAdam prescriber about trying a different birth control pill.

Page reviewed by:
Dr Daniel Atkinson
Dr Daniel Atkinson
GP Clinical Lead
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Last updated 30/03/2022


How does Cilique work?

Cilique is used to stop you from becoming unexpectedly pregnant. It works in three ways to make sure you’re protected.

The combined birth control pill alters ovulation and may stop it altogether. Ovulation is when an egg is released from your ovaries, ready for fertilisation.

Cilique also affects your uterine wall. This lining builds up and then comes away when you have your period. But the ‘period’ you have when you’re using hormonal birth control (like Cilique) isn’t the same as a normal period, because the lining doesn’t build up in the same way. It’s technically a withdrawal bleed. Women who use Cilique find that their withdrawal bleed is lighter and usually easier to deal with than a typical period.

The hormones in the pill also thicken the mucus in your cervix. This makes it harder for a sperm to reach your egg (if you are ovulating) and lowers the chances of pregnancy.

Do I need a prescription for Cilique?

Can I buy Cilique online?

How to take Cilique

The blister pack of Cilique just contains active pills. The pills are blue and are taken for 21 days, followed by a seven day break. Then start the next pack of 21 the day after that and repeat.

Start taking active pills on the first day of your period. Take them at a time that works for you (it might be first thing in the morning, for example). You don’t need to take the pill with food, but if you have an upset stomach while you’re using hormonal birth control, this might subside if you take it with food.

It’s important to take the pill at the same time every day. This makes sure the pill is as effective as possible.

Is there more than one Cilique dosage?

Is Cilique an effective birth control method?

What are the most common side effects of using Cilique?

Side effects are possible with any kind of hormonal contraception. Common Cilique pill side effects happen for as many as 1 in 100 people. The side effects will most likely go away over time, so you don’t have to worry.

You might experience headaches, stomach pain, vaginal infection and discharge. Some women have found they have tender breasts, their moods have changed, they’ve felt nervous or they have had rashes.

Taking your Cilique pill as directed will help reduce your chances of side effects.

What should I do if I have side effects on Cilique?

When do I need to see a doctor?

Cilique is also known as...

Cilest (now discontinued) and Lizinna. These pills all contain (or did contain) the same level of active ingredients as Cilique. They’re clinically the same treatment, or bio-equivalent. So they’re just as effective at preventing pregnancy as each other, and have the same side effect profile.

Cilest is no longer available. But Cilique does the same job, so if you used to take these pills, Cilique should work just as well for you.

Lizinna vs Cilique: which is better?

Is Cilique the same as Cilest?

What if I can’t take Cilique?

Cilique safety information

Before you start using Cilique, you should read through the patient information leaflet.

More info

Cilique side effects

It is possible to experience side effects when you use Cilique (or any hormonal birth control). If you have certain health conditions, it might not be a good option for you.

Stop using Cilique if you experience:

  • signs of a stroke (sudden serious headache, having trouble speaking, sudden numbness on one side of the body);
  • signs of a blood clot (sudden pains in your chest, feeling breathless, swelling in your leg or arm);
  • signs of a heart attack (chest pains, feeling weak, nausea);
  • liver problems (jaundice, abdominal pain or swelling, loss of appetite);
  • severe headaches;
  • swelling in your ankles, hands or your feet; 
  • migraines that become more severe or happen more often;
  • a lump in your breast;
  • symptoms of Cilique pill depression. These include feeling low, feeling tired, losing interest in the things you enjoyed. Mood changes are a common side effect of using Cilique. 

Very common:
Breast issues, painful periods, breakthrough or abnormal bleeding, headaches or migraines, nausea, diarrhea.

Tender or painful breasts, vaginal infection, discharge, changes to your period, urinary tract infection, missed periods, PMS symptoms, stomach pain, dizziness, rash, acne, fluctuating weight, fluid retention, back pain, mood changes.

Cilique pill weight gain is one of the most commonly reported side effects, although, for most, this is usually minimal.

Ovarian cyst, vaginal dryness, hypertension (high blood pressure), heart palpitation, shortness of breath, heavy periods, changes in sexual interest, discoloured patches of skin.

Cilique warnings


[1] Trivedi, M.K. Et al. 2017. A Review of hormone-based therapies to treat adult acne vulgaris in women. Elsevier. U.S.A. NCBI. [Accessed March 30th 2021].

[2] Cooper, D.B. and Mahdy, H. 2020. Oral Contraceptive Pills. Stat Pearls. U.S.A. NCBI. [Accessed 1st May 2021].